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  • Maria Augusta Pinheiro posted an update 3 months ago

    A MND, ou Doença do Neurônio Motor, é uma condição neurodegenerativa que afeta as células nervosas responsáveis pelo controle dos músculos voluntários. Compreender como funciona a MND é fundamental para profissionais de saúde, pacientes e familiares que lidam com este transtorno debilitante. O funcionamento desta doença envolve a degeneração progressiva dos neurônios motores, levando à fraqueza muscular e à perda de habilidades motoras. Esses sintomas afetam significativamente a qualidade de vida dos indivíduos diagnosticados, exigindo suporte contínuo e estratégias de manejo eficazes. Hidro Campo travessia não destrutiva mnd os mecanismos envolvidos na MND e os avanços na pesquisa é essencial para o desenvolvimento de tratamentos que possam melhorar a situação clínica e promover um entendimento mais amplo sobre a doença.

    O que é a Doença do Neurônio Motor?

    A Doença do Neurônio Motor, ou MND, é uma condição complexa que impacta diretamente as células nervosas responsáveis pela coordenação dos músculos voluntários. Os neurônios motores, que são essenciais para mover os músculos do corpo, começam a degenerar, resultando em dificuldades de movimento e comunicação. Essa condição pode se manifestar de diferentes formas, com a Esclerose Lateral Amiotrófica (ELA) sendo uma das mais conhecidas. A MND tem um curso progressivo, tornando-se um desafio constante para os pacientes, que enfrentam uma jornada que exige grande resiliência e um suporte contínuo. Entender como funciona MND é crucial para ajudar esses indivíduos e suas famílias.

    Os Sintomas e sua Progressão

    Os efeitos da MND sobre o corpo são variados e incluem inicialmente a fraqueza muscular, que pode se agravar com o tempo. Os pacientes podem começar a notar dificuldade para segurar objetos, falar ou até mesmo para engolir. Esse quadro pode rapidamente evoluir, levando à imobilidade e à necessidade de assistência para realizar atividades diárias. Além disso, a evolução dos sintomas pode variar consideravelmente de uma pessoa para outra, tornando o acompanhamento clínico fundamental. A identificação precoce dos sinais e a compreensão de como funciona MND permitem que os profissionais de saúde desenvolvam estratégias de manejo mais eficazes.

    Mecanismos Biológicos Subjacentes

    Os mecanismos biológicos que levam à degradação dos neurônios motores ainda são amplamente estudados. Acredita-se que uma combinação de fatores genéticos e ambientais contribua para o desenvolvimento da MND. Alterações na produção de proteínas e a acumulação de substâncias tóxicas nas células nervosas são algumas das hipóteses em investigação. O entendimento destes processos é essencial, pois elucidam como funciona MND e abrem caminhos para novas abordagens terapêuticas. Pesquisas atuais buscam identificar biomarcadores que possam ajudar no diagnóstico precoce, aumentando assim as chances de intervenções eficazes.

    Tratamento e Manejo da MND

    Ainda que não exista uma cura definitiva para a MND, diversos tratamentos visam melhorar a qualidade de vida dos pacientes. Intervenções medicamentosas, como o uso de riluzole, podem retardar a progressão da doença. Além disso, terapias ocupacionais, fisioterapia e suporte nutricional são cruciais para ajudar os pacientes a manterem a sua autonomia o máximo possível. O manejo adequado da dor e das dificuldades respiratórias também é importante para proporcionar conforto. Entender como funciona MND permite que os profissionais de saúde ofereçam cuidados personalizados, adaptando as estratégias de tratamento às necessidades de cada paciente.

    Impacto Psicológico da MND

    O diagnóstico de Doença do Neurônio Motor pode ser devastador, não apenas fisicamente, mas também emocionalmente. Muitos pacientes enfrentam sentimentos de angústia, depressão e ansiedade ao lidarem com as mudanças em suas vidas. O suporte psicológico é um componente vital no tratamento da MND, ajudando os indivíduos a enfrentarem o impacto emocional associado à progressão da doença. Grupos de apoio e aconselhamento podem fornecer um espaço seguro para compartilhar experiências e sentimentos, promovendo um ambiente de compreensão mútua. Essa dimensão psicológica complementa o conhecimento sobre como funciona MND.

    Avanços na Pesquisa e Futuras Perspectivas

    A pesquisa científica sobre a Doença do Neurônio Motor está evoluindo rapidamente, com muitos estudos focados em entender melhor os mecanismos da doença e encontrar novos tratamentos. Avanços recentes em terapias genéticas e farmacológicas mostram promessas, abrindo a possibilidade de abordagens inovadoras para o tratamento e manejo da MND. Ensaios clínicos estão em andamento para testar novas drogas que podem retardar a progressão da doença ou melhorar a função neuromuscular. A coleta de dados em larga escala está contribuindo significativamente para o entendimento de como funciona MND, possibilitando que a comunidade médica desenvolva estratégias mais eficazes para combater essa condição.

    Conclusão

    Compreender como funciona MND é essencial não apenas para o tratamento, mas também para a promoção de uma qualidade de vida adequada para os pacientes e seus familiares. Ao abordar os diversos aspectos da doença, desde os mecanismos biológicos até o impacto psicológico e as perspectivas de tratamento, é possível proporcionar um suporte mais eficaz. Com a continuação das pesquisas e a conscientização sobre esta condição, espera-se que no futuro se abra caminho para inovações que possam transformar a vida de quem convive com a MND.

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FROM wp_wfLiveTrafficHuman 
WHERE IP = '\0\0\0\0\0\0\0\0\0\0ÿÿ•úA' 
AND identifier = 'üÏ7`Væ?ûéðÎYϲ«–÷žRÜ~Óù\Z[' 
AND expiration >= UNIX_TIMESTAMP()
0.5410
SELECT option_value 
FROM wp_options 
WHERE option_name = 'cleantalk_public_script_loaded' 
LIMIT 1
0.5081
SELECT option_value 
FROM wp_options 
WHERE option_name = 'pd_map_open_street_map' 
LIMIT 1
0.6309
SELECT option_value 
FROM wp_options 
WHERE option_name = 'pd_enable_rtl' 
LIMIT 1
0.2680
SELECT option_value 
FROM wp_options 
WHERE option_name = 'pd_lan_view_site' 
LIMIT 1
0.5820
SELECT option_value 
FROM wp_options 
WHERE option_name = 'sharing-services' 
LIMIT 1
1.1230
SHOW FULL COLUMNS 
FROM `wp_wfHits`
0.7331
INSERT INTO `wp_wfHits` (`ctime`, `statusCode`, `isGoogle`, `IP`, `userID`, `URL`, `referer`, `UA`, `jsRun`) VALUES ('1732439800.197769', '200', '0', '\0\0\0\0\0\0\0\0\0\0ÿÿ•úA', '0', 'https://thefreegiftofgod.today/members/smashblade7/activity/122057/', 'https://thefreegiftofgod.today/members/smashblade7/activity/122057', 'Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)', '')
0.3901
select HEX(AES_ENCRYPT('170376', '7481b0912699bbab')) as val
1.7540
SELECT `wp_postmeta`.`post_id`, `wp_postmeta`.`meta_value`, `wp_posts`.`post_type` 
FROM `wp_posts`, `wp_postmeta` 
WHERE `wp_posts`.`ID` = `wp_postmeta`.`post_id` 
AND `wp_postmeta`.`meta_key` = 's2member_ccaps_req' 
AND `wp_postmeta`.`meta_value` != ''
0.8581
SELECT `ID` 
FROM `wp_posts` 
WHERE `post_status` = 'publish' 
AND `post_type` = 'topic' 
AND `post_parent` IN('109')
1.1442
SELECT wp_posts.ID 
FROM wp_posts 
WHERE 1=1 
AND wp_posts.ID NOT IN (44,109,87) 
AND wp_posts.post_parent = 0 
AND (wp_posts.post_mime_type LIKE 'image/%') 
AND wp_posts.post_type = 'attachment' 
AND ((wp_posts.post_status = 'inherit')) 
ORDER BY wp_posts.post_date DESC 
LIMIT 0, 5
0.8419
SELECT wp_posts.* 
FROM wp_posts 
WHERE ID IN (850,813,415,370,369)
1.2331
SELECT post_id, meta_key, meta_value 
FROM wp_postmeta 
WHERE post_id IN (850,813,415,370,369) 
ORDER BY meta_id ASC
0.5958
SELECT option_value 
FROM wp_options 
WHERE option_name = 'https_migration_required' 
LIMIT 1
0.5610
SELECT * 
FROM wp_posts 
WHERE ID = 694 
LIMIT 1
2.2180
SELECT `wp_postmeta`.`post_id`, `wp_postmeta`.`meta_value`, `wp_posts`.`post_type` 
FROM `wp_posts`, `wp_postmeta` 
WHERE `wp_posts`.`ID` = `wp_postmeta`.`post_id` 
AND `wp_postmeta`.`meta_key` = 's2member_ccaps_req' 
AND `wp_postmeta`.`meta_value` != ''
0.4730
SELECT `ID` 
FROM `wp_posts` 
WHERE `post_status` = 'publish' 
AND `post_type` = 'topic' 
AND `post_parent` IN('109')
0.9351
SELECT wp_posts.ID 
FROM wp_posts 
WHERE 1=1 
AND wp_posts.ID NOT IN (44,109,87) 
AND wp_posts.post_parent = 0 
AND wp_posts.post_type = 'page' 
AND ((wp_posts.post_status = 'publish')) 
ORDER BY wp_posts.post_title ASC 
LIMIT 0, 1
0.4251
SELECT wp_posts.* 
FROM wp_posts 
WHERE ID IN (104)
0.3071
SELECT option_value 
FROM wp_options 
WHERE option_name = 'site_logo' 
LIMIT 1
0.7119
SELECT DISTINCT t.term_id 
FROM wp_terms AS t 
INNER JOIN wp_term_taxonomy AS tt ON t.term_id = tt.term_id 
INNER JOIN wp_term_relationships AS tr ON tr.term_taxonomy_id = tt.term_taxonomy_id 
WHERE tt.taxonomy IN ('bp_member_type') 
AND tr.object_id IN (193557) 
ORDER BY t.name ASC
0.4470
SELECT t.*, tt.* 
FROM wp_terms AS t 
INNER JOIN wp_term_taxonomy AS tt ON t.term_id = tt.term_id 
WHERE t.term_id = 2
0.8500
SELECT `wp_postmeta`.`post_id`, `wp_postmeta`.`meta_value`, `wp_posts`.`post_type` 
FROM `wp_posts`, `wp_postmeta` 
WHERE `wp_posts`.`ID` = `wp_postmeta`.`post_id` 
AND `wp_postmeta`.`meta_key` = 's2member_ccaps_req' 
AND `wp_postmeta`.`meta_value` != ''
0.4210
SELECT `ID` 
FROM `wp_posts` 
WHERE `post_status` = 'publish' 
AND `post_type` = 'topic' 
AND `post_parent` IN('109')
1.3850
SELECT wp_posts.* 
FROM wp_posts LEFT JOIN wp_term_relationships ON (wp_posts.ID = wp_term_relationships.object_id) 
WHERE 1=1 
AND wp_posts.ID NOT IN (44,109,87) 
AND ( wp_term_relationships.term_taxonomy_id IN (2) ) 
AND wp_posts.post_type = 'nav_menu_item' 
AND ((wp_posts.post_status = 'publish')) 
GROUP BY wp_posts.ID 
ORDER BY wp_posts.menu_order ASC
1.7540
SELECT post_id, meta_key, meta_value 
FROM wp_postmeta 
WHERE post_id IN (163,141,142,143,51,66,592,74,84,573,595,158,50,260,159,824) 
ORDER BY meta_id ASC
0.6521
SELECT wp_posts.* 
FROM wp_posts 
WHERE ID IN (161,98,100,102,5,64,590,42,81,497,593,21,231,107,821)
1.7400
SELECT post_id, meta_key, meta_value 
FROM wp_postmeta 
WHERE post_id IN (161,98,100,102,5,64,590,42,81,497,593,104,21,231,107,821) 
ORDER BY meta_id ASC
0.7200
SELECT t.*, tt.* 
FROM wp_terms AS t 
INNER JOIN wp_term_taxonomy AS tt ON t.term_id = tt.term_id 
WHERE t.term_id = 5
0.8969
SELECT `wp_postmeta`.`post_id`, `wp_postmeta`.`meta_value`, `wp_posts`.`post_type` 
FROM `wp_posts`, `wp_postmeta` 
WHERE `wp_posts`.`ID` = `wp_postmeta`.`post_id` 
AND `wp_postmeta`.`meta_key` = 's2member_ccaps_req' 
AND `wp_postmeta`.`meta_value` != ''
0.4611
SELECT `ID` 
FROM `wp_posts` 
WHERE `post_status` = 'publish' 
AND `post_type` = 'topic' 
AND `post_parent` IN('109')
1.2729
SELECT wp_posts.* 
FROM wp_posts LEFT JOIN wp_term_relationships ON (wp_posts.ID = wp_term_relationships.object_id) 
WHERE 1=1 
AND wp_posts.ID NOT IN (44,109,87) 
AND ( wp_term_relationships.term_taxonomy_id IN (6) ) 
AND wp_posts.post_type = 'nav_menu_item' 
AND ((wp_posts.post_status = 'publish')) 
GROUP BY wp_posts.ID 
ORDER BY wp_posts.menu_order ASC
1.5290
SELECT post_id, meta_key, meta_value 
FROM wp_postmeta 
WHERE post_id IN (214,215,216,217,218,219,220,221,222,223,224,225) 
ORDER BY meta_id ASC
0.5460
SELECT post_id, meta_key, meta_value 
FROM wp_postmeta 
WHERE post_id IN (213,123,122) 
ORDER BY meta_id ASC
0.4311
SELECT DISTINCT a.id 
FROM wp_bp_activity a 
WHERE a.id IN (122057) 
AND a.type NOT IN ('activity_comment', 'last_activity') 
ORDER BY a.date_recorded DESC, a.id DESC 
LIMIT 0, 21
0.2549
SELECT wp_users.ID,wp_users.user_login,wp_users.user_pass,wp_users.user_nicename,wp_users.user_email,wp_users.user_url,wp_users.user_registered,wp_users.user_activation_key,wp_users.user_status,wp_users.display_name 
FROM wp_users 
WHERE 1=1 
AND wp_users.ID IN (193557) 
ORDER BY user_login ASC
0.3400
SELECT id 
FROM wp_bp_activity a 
WHERE a.type = 'activity_comment' 
AND a.item_id = 122057 and a.mptt_left > 0 
AND a.mptt_left < 0 
ORDER BY a.date_recorded ASC
0.4830
SELECT * 
FROM `wp_wysija_form` 
WHERE form_id IN ("1") 
ORDER BY form_id DESC 
LIMIT 0 , 1
0.5429
SELECT name, list_id, is_public 
FROM `wp_wysija_list` 
WHERE is_enabled=1 
ORDER BY list_id DESC
0.4811
SELECT option_value 
FROM wp_options 
WHERE option_name = '_transient_timeout_wpcom_subscribers_total' 
LIMIT 1
0.3841
SELECT option_value 
FROM wp_options 
WHERE option_name = '_transient_wpcom_subscribers_total' 
LIMIT 1
0.4780
SELECT t.*, tt.* 
FROM wp_terms AS t 
INNER JOIN wp_term_taxonomy AS tt ON t.term_id = tt.term_id 
WHERE t.term_id = 7
0.8969
SELECT `wp_postmeta`.`post_id`, `wp_postmeta`.`meta_value`, `wp_posts`.`post_type` 
FROM `wp_posts`, `wp_postmeta` 
WHERE `wp_posts`.`ID` = `wp_postmeta`.`post_id` 
AND `wp_postmeta`.`meta_key` = 's2member_ccaps_req' 
AND `wp_postmeta`.`meta_value` != ''
0.4349
SELECT `ID` 
FROM `wp_posts` 
WHERE `post_status` = 'publish' 
AND `post_type` = 'topic' 
AND `post_parent` IN('109')
0.9632
SELECT wp_posts.* 
FROM wp_posts LEFT JOIN wp_term_relationships ON (wp_posts.ID = wp_term_relationships.object_id) 
WHERE 1=1 
AND wp_posts.ID NOT IN (44,109,87) 
AND ( wp_term_relationships.term_taxonomy_id IN (3) ) 
AND wp_posts.post_type = 'nav_menu_item' 
AND ((wp_posts.post_status = 'publish')) 
GROUP BY wp_posts.ID 
ORDER BY wp_posts.menu_order ASC
0.4821
SELECT post_id, meta_key, meta_value 
FROM wp_postmeta 
WHERE post_id IN (228) 
ORDER BY meta_id ASC
0.3119
SELECT option_value 
FROM wp_options 
WHERE option_name = 'cookie_consent_template' 
LIMIT 1
Templates
[0] => themes/mh_magazine/includes/mh-breadcrumb.php
[1] => themes/mh_magazine/includes/mh-post-content.php
[2] => themes/mh_magazine/includes/mh-options.php
[3] => themes/mh_magazine/includes/mh-widgets.php
[4] => themes/mh_magazine/includes/widgets/mh-facebook-likebox.php
[5] => themes/mh_magazine/includes/widgets/mh-custom-posts.php
[6] => themes/mh_magazine/includes/widgets/mh-custom-pages.php
[7] => themes/mh_magazine/includes/widgets/mh-nip.php
[8] => themes/mh_magazine/includes/widgets/mh-comments.php
[9] => themes/mh_magazine/includes/widgets/mh-slider.php
[10] => themes/mh_magazine/includes/widgets/mh-custom-slider.php
[11] => themes/mh_magazine/includes/widgets/mh-spotlight.php
[12] => themes/mh_magazine/includes/widgets/mh-carousel.php
[13] => themes/mh_magazine/includes/widgets/mh-authors.php
[14] => themes/mh_magazine/includes/widgets/mh-social-widget.php
[15] => themes/mh_magazine/includes/widgets/mh-affiliate.php
[16] => themes/mh_magazine/includes/widgets/mh-advertising-widget.php
[17] => themes/mh_magazine/includes/mh-custom-functions.php
[18] => themes/mh_magazine/includes/mh-google-webfonts.php
[19] => themes/mh_magazine/includes/mh-social.php
[20] => themes/mh_magazine/includes/mh-advertising.php
[21] => themes/mh_magazine/includes/mh-shortcodes.php
[22] => themes/mh_magazine/page.php
[23] => themes/mh_magazine/header.php
[24] => themes/mh_magazine/content-page.php
[25] => themes/mh_magazine/comments-pages.php
[26] => themes/mh_magazine/sidebar.php
[27] => themes/mh_magazine/footer.php
[28] => themes/mh_magazine/searchform.php
Globals
$_GET = array (
);

$_POST = array (
);

$_COOKIE = array (
  'ct_sfw_pass_key' => '288e1f2dd481b394d4532fd5954647140',
  'apbct_site_landing_ts' => '1732439799',
  'apbct_cookies_test' => '{\\"cookies_names\\":[\\"apbct_timestamp\\",\\"apbct_site_landing_ts\\",\\"apbct_page_hits\\"],\\"check_value\\":\\"3f964af977b95f4d348240ff2f124aa2\\"}',
  'apbct_urls' => '{\\"thefreegiftofgod.today/members/smashblade7/activity/122057\\":[1732439799]}',
  'pdb-sess' => 'e698815b1ab60db04213a1138ed038fd',
  'apbct_timestamp' => '1732439799',
  'apbct_page_hits' => '1',
  'apbct_site_referer' => 'UNKNOWN',
);

$_SESSION = array (
);

$_SERVER = array (
  'SERVER_SOFTWARE' => 'Apache',
  'REQUEST_URI' => '/members/smashblade7/activity/122057/',
  'LSPHP_ENABLE_USER_INI' => 'on',
  'PATH' => '/usr/local/bin:/usr/bin:/bin',
  'TEMP' => '/tmp',
  'TMP' => '/tmp',
  'TMPDIR' => '/tmp',
  'PWD' => '/',
  'HTTP_ACCEPT' => '*/*',
  'HTTP_ACCEPT_ENCODING' => 'gzip, br, zstd, deflate',
  'CONTENT_LENGTH' => '0',
  'HTTP_COOKIE' => 'ct_sfw_pass_key=288e1f2dd481b394d4532fd5954647140; apbct_site_landing_ts=1732439799; apbct_cookies_test=%7B%22cookies_names%22%3A%5B%22apbct_timestamp%22%2C%22apbct_site_landing_ts%22%2C%22apbct_page_hits%22%5D%2C%22check_value%22%3A%223f964af977b95f4d348240ff2f124aa2%22%7D; apbct_urls=%7B%22thefreegiftofgod.today%2Fmembers%2Fsmashblade7%2Factivity%2F122057%22%3A%5B1732439799%5D%7D; pdb-sess=e698815b1ab60db04213a1138ed038fd; apbct_timestamp=1732439799; apbct_page_hits=1; apbct_site_referer=UNKNOWN',
  'HTTP_HOST' => 'thefreegiftofgod.today',
  'HTTP_REFERER' => 'https://thefreegiftofgod.today/members/smashblade7/activity/122057',
  'HTTP_USER_AGENT' => 'Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)',
  'HTTP_X_HTTPS' => '1',
  'REDIRECT_UNIQUE_ID' => 'Z0Lu-EAc43wxbKxa6dIm3gAAL2U',
  'REDIRECT_QS_ConnectionId' => '173243980007352233455880',
  'REDIRECT_SCRIPT_URL' => '/members/smashblade7/activity/122057/',
  'REDIRECT_SCRIPT_URI' => 'https://thefreegiftofgod.today/members/smashblade7/activity/122057/',
  'REDIRECT_HTTP_AUTHORIZATION' => '',
  'REDIRECT_HTTPS' => 'on',
  'REDIRECT_SSL_TLS_SNI' => 'thefreegiftofgod.today',
  'REDIRECT_HTTP2' => 'on',
  'REDIRECT_H2PUSH' => 'off',
  'REDIRECT_H2_PUSH' => 'off',
  'REDIRECT_H2_PUSHED' => '',
  'REDIRECT_H2_PUSHED_ON' => '',
  'REDIRECT_H2_STREAM_ID' => '3',
  'REDIRECT_H2_STREAM_TAG' => '455880-1559-3',
  'REDIRECT_STATUS' => '200',
  'UNIQUE_ID' => 'Z0Lu-EAc43wxbKxa6dIm3gAAL2U',
  'QS_ConnectionId' => '173243980007352233455880',
  'SCRIPT_URL' => '/members/smashblade7/activity/122057/',
  'SCRIPT_URI' => 'https://thefreegiftofgod.today/members/smashblade7/activity/122057/',
  'HTTP_AUTHORIZATION' => '',
  'HTTPS' => 'on',
  'SSL_TLS_SNI' => 'thefreegiftofgod.today',
  'HTTP2' => 'on',
  'H2PUSH' => 'off',
  'H2_PUSH' => 'off',
  'H2_PUSHED' => '',
  'H2_PUSHED_ON' => '',
  'H2_STREAM_ID' => '3',
  'H2_STREAM_TAG' => '455880-1559-3',
  'SERVER_SIGNATURE' => '',
  'SERVER_NAME' => 'thefreegiftofgod.today',
  'SERVER_ADDR' => '192.185.138.104',
  'SERVER_PORT' => '443',
  'REMOTE_ADDR' => '3.149.250.65',
  'DOCUMENT_ROOT' => '/home1/freegift/public_html',
  'REQUEST_SCHEME' => 'https',
  'CONTEXT_PREFIX' => '',
  'CONTEXT_DOCUMENT_ROOT' => '/home1/freegift/public_html',
  'SERVER_ADMIN' => 'webmaster@thefreegiftofgod.today',
  'SCRIPT_FILENAME' => '/home1/freegift/public_html/index.php',
  'REMOTE_PORT' => '36590',
  'REDIRECT_URL' => '/members/smashblade7/activity/122057/',
  'SERVER_PROTOCOL' => 'HTTP/2.0',
  'REQUEST_METHOD' => 'GET',
  'QUERY_STRING' => '',
  'SCRIPT_NAME' => '/index.php',
  'PHP_SELF' => '/index.php',
  'REQUEST_TIME_FLOAT' => 1732439800.08658695220947265625,
  'REQUEST_TIME' => 1732439800,
  'argv' => 
  array (
  ),
  'argc' => 0,
);

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